MEDIA PRESENCE OF TKTL1

It controls cell division and plays a crucial role in the development of the brain: TKTL1 has rightly been the focus of science and research for several years. It could also revolutionize the early detection and treatment of cancer. The discoverer of the gene, Dr. Johannes Coy, explains.

Science is blazing innovative trails in early cancer detection by studying molecular and genetic indicators of cancer. New methods such as a Swedish test that identifies 14 types of cancer through sugar compounds or the PanTum Detect® blood test that analyses macrophages from the blood are raising hopes for earlier and more accurate diagnoses.

In an exclusive interview with NORD WIRTSCHAFT, Folke Tedsen, Head of Benefit and Health Management at HanseMerkur, presents the new supplemental insurance program “Krebs-Scan”. This innovative approach uses the unique PanTum Detect® blood test in combination with imaging techniques to detect potentially dangerous tumors at an early stage. Tedsen discusses the development of the program, the underlying research and the costs for customers, highlighting the potential importance of this innovation for cancer prevention in Germany.

Liquid biopsies are a promising innovation in cancer detection, despite existing challenges such as the improvement of reliability and recognition by health insurers. In this context, the Hessian company Zyagnum AG is doing pioneering work. Its blood-based cancer screening test is the first to be reimbursed by a German private insurance company, Hanse Merkur. This advance is a significant step towards personalized medicine and could have a decisive impact on the future of oncology.

The PanTum Detect® blood test for early cancer detection is reimbursed for the first time by a private health insurance company, HanseMerkur. This breakthrough is based on encouraging study results that shed light on the possibility of early tumor diagnosis. Criticism comes from the medical community: among other things, the risk of false positive test results is pointed out, which is said to be a high psychological burden for those affected.

HanseMerkur Insurance Group is integrating the blood test PanTum Detect® into its new cancer early detection program “Krebs-Scan”. The test, developed by Zyagnum AG, is able to detect certain enzymes produced by most tumors at early stages. Together with modern imaging techniques, this program enables a more comprehensive early cancer detection.

New research shows differences in the structure of the brain between that of modern humans and that of Neanderthals, particularly with regard to the protein TKTL1, which varies by a point mutation, resulting in a higher number of neurons in modern humans. It is reasonable to assume that TKTL1 and the resulting brain cells are important for human thought.

A genetic change in modern humans promotes the production of more neurons, in particular due to a modern variant of the protein TKTL1 that differs from the Neanderthal version by a single amino acid. Researchers at the Max Planck Institute of Cell and Molecular Biology and Genetics have found that this variation boosts the number of neural progenitor cells in the neocortex, an area of the brain that is critical for cognition. This discovery raises new questions about the biological keys that define us as humans and are at the origin of our unique cognitive abilities. 

A simple change in the composition of a protein in the brain could explain the difference in neuron production in the front part of our cortex compared to Neanderthals. Researchers at Max Planck Institutes in Germany have discovered a difference between our genome and that of Neanderthals which could point to increased cognitive abilities. The protein TKTL1, which has one amino acid different in the human version, plays a central role. 

A crucial difference in brain development between Neanderthals and modern humans has been uncovered by a German research team. Neanderthals produced neural stem cells that were more prone to errors and less efficient at producing neurons. These findings offer insights into the higher cognitive performance of modern humans and may provide the key to understanding the extinction of Neanderthals.

A study highlights the role of the protein TKTL1 in the development of the human brain. Compared to the Neanderthal version, human TKTL1 promotes the formation of more neurons in the neocortex. This finding could help explain the cognitive superiority of modern humans over Neanderthals.

Scientists have discovered that a variation in the TKTL1 protein in the brain plays a role in the development of neurons. These findings could help explain the difference in cognitive abilities between modern humans and Neanderthals. 

Researchers have found that TKTL1 in the frontal lobe of the brain promotes the formation of neurons. These findings help to better understand the differences in brain development between modern humans and Neanderthals and shed light on the evolutionary factors that have led to our intellectual superiority.

Researchers in Dresden may have identified a crucial moment in the evolution of Homo sapiens that took place several hundred thousand years ago. A tiny mutation could be the key to human evolution. This discovery sheds new light on the evolution of our brain and the unique features that distinguish us as a species.

Tiny genetic changes in the TKTL1 gene may have given modern humans a crucial advantage by enabling the formation of a greater number of neurons in the brain’s neocortex. An international group of researchers led by Anneline Pinson at the Max Planck Institute for Molecular Cell Biology and Genetics has found that a single amino acid change in the TKTL1 protein sequence is present in modern humans when compared to Neanderthals.

Various studies conducted by Max Planck Institute show that Neanderthals had fewer neurons than modern humans despite similar brain size, due to a single protein mutation. This sheds new light on the evolution of human cognitive abilities and the role of minimal genetic differences.

Researchers at Max Planck Institute reveal that a minimal change in the protein TKTL1 causes the increased neuron formation in the brains of modern humans compared to Neanderthals. This finding provides deep insights into the intricacies of human brain evolution and the formation of our cognitive abilities.

According to a study by the Max Planck Institute, a marginal change in the protein TKTL1 leads to a significantly increased neuron formation in modern humans compared to Neanderthals. This genetic difference provides new insights into the fine-tuning of our brain development and the complexity of human cognition.

Researchers at Dresden’s Max Planck Institute of Molecular Cell Biology and Genetics identify a crucial gene mutation responsible for the unique development of the human brain. This change is missing in Neanderthals as well as in all animal species.

A study by Tübingen’s Eberhard Karls University shows that PanTum Detect® blood test can detect elevated levels of the tumor markers TKTL1 and DNaseX (Apo10) in 94.7% of the examined children and adolescents with neuroblastoma.

A study at Eppendorf University Hospital investigates the use of the PanTum Detect® blood test for early cancer detection in combination with imaging procedures. The results show that malignant tumors or premalignant lesions were identified in subsequent imaging in 82 percent of participants who tested conspicuously in the blood test.